A system for determining occurrence time of sleep stage by integrating physiology cycle and a method thereof are provided. By calculating an integrated physiology data using characteristic of each measured physiology data, and determining occurrence time of each sleep stage based on the integrated physiology data, the system and the method can determine sleep stage accurately, and can achieve the effect of determining what sleep stage is on specific time.一種整合生理週期以判斷睡眠階段進入時間之系統及其方法,其透過由所測得之受測生理資料的個別特徵計算整合生理資料,並依據整合生理資料的整體特徵判斷各睡眠階段之起始時間的技術手段,可以較準確的判斷睡眠階段,並達成判斷特定時間之睡眠階段的技術功效。步驟310 提供受測者於一次睡眠中所測得之多個受測生理資料步驟330 讀取受測生理資料步驟350 依據各受測生理資料中對應之同步變化調整各受測生理資料之相位步驟360 依據各受測生理資料之個別特徵計算整合生理資料步驟370 計算整合生理資料之整體特徵步驟380 依據整體特徵判斷睡眠中進入各睡眠階段之起始時間步驟390 依據各睡眠階段之起始時間判斷睡眠中任意時間點之睡眠階段