Chang-Shan HSU,Wei-Hua HAO,Jong-Jing WANG,Tsung-Hsin LIN
申请号:
US14669233
公开号:
US20150196537A1
申请日:
2015.03.26
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention provides an oral self micro-emulsifying pharmaceutical composition of a hydrophilic drug or a pharmaceutically acceptable salt thereof which, in addition to the hydrophilic drug, one or more solvents for solving the hydrophilic drug to form a drug-solvent solution and a surfactant system, further comprises one or more hydrophilic carrier which are compatible with said drug-solvent solution and the surfactant system. The oral self micro-emulsifying pharmaceutical composition of the invention exhibits comparative bioavailability to that of the hydrophilic drug through injection and is stable during storage. A method for preparing the oral self micro-emulsifying pharmaceutical composition is also provided.