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COMBINATION THERAPY OF HBV AND HDV INFECTION
专利权人:
MYR GMBH
发明人:
ALEXANDROV, ALEXANDER
申请号:
CA2959465
公开号:
CA2959465A1
申请日:
2015.10.07
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
The invention provides a composition comprising an inhibitor of Na+-taurocholate cotransporting polypeptide (NTCP) and a active ingredient selected from the group consisting of a nucleoside analogue such as lamivudine, telbivudine, or entecavir, a nucleotide analogue such as tenofovir, adefovir and an immunomodulator such as interferon alpha. The NTCP inhibitor inhibits HBV/HDV entry into a cell and is preferably derived from an HBV pre-S1 peptide. Also provided are methods of treating HBV and HDV infection, hepatitis B and D, or chronic hepatitis B and D.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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