The present invention relates to a device for ultrasonic-accelerated hematoma lysis or thrombolysis of intracerebral or intraventricular hemorrhages or hematomas, comprising a body (20) which accommodates a number of separated compartments or lumens consisting of- a flushing catheter (1) for flushing fluid and/or pharmaceutically active substances into the intracerebral or intraventricular hemorrhages or hematomas,- a drainage catheter (2) for draining fluid from the intracerebral or intraventricular hemorrhages or hematomas,- an ultrasonic probe duct (3), and- a pressure sensor duct (5),wherein the compartments or lumens are arranged in proximity to each other and wherein in longitudinal extension at least upper-part sections of the compartments or lumens are isolated by walls, wherein the lumen of the pressure sensor duct (5) integrates a pressure sensor (6), and wherein in the lumen of ultrasonic probe duct (3) an endosonographic probe (4) or a stiletto (13) is interchangeably guided.