A blood sugar measuring device with a compensation bias circuit, given in the present invention, includes a test strip into which the blood of an examinee is inputted an amplification unit which amplifies the current generated from the charges of the blood into a voltage a first A/D conversion unit which converts the analog signal of the blood voltage amplified by the amplification unit into a digital signal a fixed bias circuit to which a certain voltage is supplied in phases a bias control unit which includes a compensation circuit to output a compensation voltage, if the fixed voltage outputted from the fixed bias circuit is different from a preset voltage, in order to make the voltage identical to the preset voltage a second A/D conversion unit which converts the analog signals of the fixed voltage and the compensation voltage into digital signals a D/A conversion unit which converts the digital signals of the voltages supplied to the fixed bias circuit and the compensation bias circuit into analog signals a central processing unit which recognizes the insertion of the test strip, delivers to the D/A conversion unit a digital signal which raises the voltage supplied to the fixed bias circuit in phases to make the fixed voltage identical to the preset voltage when the test strip is recognized, cuts the fixed voltage by the blood voltage if the fixed voltage delivered through the second A/D conversion unit is the same as the preset voltage, or increases or decreases the voltage supplied to the compensation circuit if the digital signal of the fixed voltage is not the same as the preset voltage in order to make the fixed voltage identical to the preset voltage using the compensation voltage and a display unit which displays the value where the blood voltage is subtracted from the sum of the fixed voltage and the compensation voltage.COPYRIGHT KIPO 2014[Reference numerals] (100) Test strip(200) Amplification unit(300) First A/D conversion unit(400) Bias control unit