Daniel C. Wadsworth, JR.;Allen B. Kantrowitz;Chris Mortis
发明人:
Allen B. Kantrowitz,Chris Mortis,Daniel C. Wadsworth, JR.
申请号:
US13394239
公开号:
US20120310181A1
申请日:
2011.02.23
申请国别(地区):
US
年份:
2012
代理人:
摘要:
A device for reducing agent penetration at an insertion site is provided that has a porous inner sleeve fluidly connected to a conduit. A vacuum or hydrodynamic source is fluidly connected to the conduit. The device is stabilized by fibroblast in-growth and inhibits bacterial colonization. A device is also provided that has a conduit having a bore and an outer conduit surface. The outer conduit surface is optionally nanotextured to promote fibroblast adhesion and limit bacterial residency. A sleeve is provided in fluid communication with the bore of the conduit, and is formed from materials characterized by a pore matrix through which vacuum or hydrodynamic draw is achieved in a process to promote stabilization and reducing bacterial colonization by draw fluid from an area around the surrounding the site of the device. The sleeve optionally has a distal nanotextured surface.