A disposable pre-filled syringe has a protecting tube (10), a medication filling tube (20), a separating plug (30), a pushing module (40), and a needle module (50). The medication filling tube (20) is made of material stable in chemical property and is mounted in the protecting tube (10). The separating plug (30) is mounted in an end of the medication filling tube (20). The pushing module (40) is slidably inserted into the medication filling tube (20) opposite to the separating plug (30). The needle module (50) is mounted on an end of the protecting tube (10).
