KING DALTON U S A,MENG ZHAOXING U S A,MCDONALD IVAR U S A,OLSON RICHARD E U S A,MACOR JOHN E U S A
申请号:
IN6921/DELNP/2011
公开号:
IN2011DN06921A
申请日:
2011.09.09
申请国别(地区):
IN
年份:
2012
代理人:
摘要:
Disclosed are compounds, pharmaceutical compositions containing the compounds, methods for using the compounds and processes for making the compounds. More specifically, the disclosure relates to alpha-(N-benzenesulfonamido)cycloalkyl compounds that may inhibit one or both of: (i) the functioning of a γ-secretase enzyme or (ii) the production of -amyloid. Such compounds may be beneficial in the treatment of Alzheimers disease and other conditions. Representative compounds have the following formula (I) wherein: A, R1, and R2 are described herein.