A mask for patient ventilation that includes a frame for surrounding a respiratory opening of a patient and forming a cavity between an inner surface of the mask and the patient. The frame forms an access aperture that can enable access to the cavity and any of a nose and a mouth region of the patient without requiring removal of the mask or frame from the patient. A removable insert can be attached and detached from the frame without requiring removal of the mask or frame from the patient. When attached to the frame, the removable insert can obstruct the access aperture and form a portion of the cavity.