Leah M. Fung,Kyle W.H. Chan,Robert W. Sullivan,Cathy A. Swindlehurst
申请号:
US15806952
公开号:
US20180127359A1
申请日:
2017.11.08
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Provided herein are nitrite salts of 1,1-dimethylbiguanide; and isotopic variants thereof; and pharmaceutically acceptable hydrates and solvates thereof. Also provided herein are their pharmaceutical compositions and methods of use for treating, preventing, or ameliorating one or more symptoms of diseases associated with and/or caused by an abnormal blood glucose level. Further provided herein are methods of their use for treating, preventing, or ameliorating one or more symptoms of a cardiovascular disease.