The invention relates to a transdermal therapeutic system (TTS)that is essentially composed of two compartments and that isprovided with activatable oversaturation and controlled permeationpromotion. The invention more particularly relates to a TTSwherein an oversaturated active ingredient solution is producedin an active-substance-containing polymer matrix when the systemis applied to the skin, caused by the controlled supply of oneor several substances promoting the permeation of the pharmaceuticalactive ingredient； to the two compartments from which theinventive transdermal therapeutic system is assembled； and tothe production of said transdermal therapeutic system from thetwo compartments.
