A drug injection device is disclosed. A drug injection device, according to the present invention, comprises: a plunger which is connected to an ampoule filled with an injectable solution and applies pressure to the injectable solution in the ampoule; a manual plunger handle which is connected to one side of the plunger and manually applies pressure to the plunger; and an automatic plunger pressurizing unit which is selectively connected to the plunger in a position adjacent to same and automatically applies pressure to same by means of power.