Recombinant anti-epidermal growth factor receptor antibody compositions

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专利权人:

SYMPHOGEN A/S

发明人:

PEDERSEN, MIKKEL WANDAHL,STEINAA, LUCILLA,JENSEN, ALLAN,KOEFOED, KLAUS,MEIJER, PER-JOHAN,CARLSSON, ROBERT,PYKE, CHARLES,NIELSEN, LARS SOEGAARD

申请号：

NZ59746608

公开号：

NZ597466A

申请日:

2008.02.27

申请国别(地区):

NZ

年份:

2013

代理人:

摘要：

597466 Disclosed is an anti-EGFR antibody or an antigen-binding fragment thereof, comprising the heavy chain CDR1, CDR2, and CDR2 amino acid sequences in SEQ ID NO: 50 and the light chain CDR1, CDR2, and CDR2 amino acid sequences in SEQ ID NO: 82 wherein SEQ ID NO: 50 is: RAEVQLVESGGGLVKPGESLKLSCAASGFAFSYSDMSWVRQTPEKRLEWVAYMSSAGDVTFYSDTVKGRFTISRDNAKNTLYLQVSSLKSEDTAIYYCVRHRDVAMDYWGQGTSVTVS and SEQ ID NO: 82 is: LADVVMTQTPLSLPVSLGDQASISCRSSQSLVHSNGNTYLHWYLQKPGQSPKLLIYKVSNRFSGVPDRFSGSGSGTDFTLKISRVEAEDLGVYFCSQSTHVPTFGGGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC.

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中国工程科技知识中心

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