Stephane Peluso;Vesa Nevalainen;Thomas T. Tibbitts;Marta Nevalainen;Lawrence K. Chan;Alfredo C. Castro;Daniel A. Snyder;Adilah Bahadoor;Gregg F. Keaney
发明人:
Adilah Bahadoor,Alfredo C. Castro,Lawrence K. Chan,Gregg F. Keaney,Marta Nevalainen,Vesa Nevalainen,Stephane Peluso,Daniel A. Snyder,Thomas T. Tibbitts
申请号:
US13101978
公开号:
US08546432B2
申请日:
2011.05.05
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Provided herein are tetrazolone FASN inhibitors of the formula (I):or a pharmaceutically acceptable form thereof; wherein the variables RA, RB and RC are defined herein.Also provided herein are pharmaceutical compositions of the compounds provided herein as well as methods of their use for the treatment of various disorders such as hyperproliferative disorders, inflammatory disorders, obesity-related disorders and microbial infections.