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COMPOSES CYCLOALKYLE-ETHER ET LEUR UTILISATION EN TANT QU'INHIBITEURS DE BACE
专利权人:
ASTRAZENECA AB
发明人:
KARLSTROM, SOFIA,SODERMAN, PETER,SWAHN, BRITT-MARIE,RAKOS, LASZLO,OHBERG, LISELOTTE
申请号:
CA2874950
公开号:
CA2874950A1
申请日:
2013.06.20
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
Cycloalkyl ether compounds, therapeutically acceptable salts thereof, processes for preparation thereof, therapeutic uses of such compounds for treating ?ß-related pathologies such as Down's syndrome, ß-amyloid angiopathy, Alzheimer's disease, memory loss, attention deficit symptoms associated with Alzheimer's disease, neurodegeneration associated with diseases such as Alzheimer's disease or dementia including dementia of mixed vascular and degenerative origin, pre-senile dementia, senile dementia and dementia associated with Parkinson's disease, progressive supranuclear palsy or cortical basal degeneration and pharmaceutical compositions containing such compounds. Formula (I) wherein A is -O-, or -CH2-, n is 0 or 1.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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