ANTONIO A. ALBANO,WANTANEE PHUAPRADIT,NAVNIT HARGOVINDAS SHAH,ZHONGSHUI YU,LIN ZHANG
申请号：
BRPI0719880
公开号：
BRPI0719880A2
申请日:
2007.10.04
申请国别(地区):
BR
年份:
2014
代理人:
摘要：
The present invention provides novel pharmaceutical solid dosage forms for oral administration comprising a therapeutically effective amount of an unstable crystalline form or an amorphous form of a therapeutically effective compound micro-embedded into an ionic water-insoluble polymer. The therapeutically effective compounds, which have a tendency to gel, are micro-embedded into an ionic water-insoluble polymer matrix to provide a dosage form having rapid, reproducible, and complete dissolution profiles. These novel solid pharmaceutical dosage forms are useful in the treatment or control of a number of diseases. The present invention also provides a method for treating a disease comprising administering to a subject, in need thereof, a therapeutically effective amount of the novel solid pharmaceutical dosage form. The present invention further provides a method for preparing the pharmaceutical dosage forms.
