Charlotte McDonagh,Paul Carter,Julie McEarchern,Che-Leung Law
申请号：
US13271143
公开号：
US08562987B2
申请日:
2011.10.11
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Disclosed are CD70 binding agents, such as humanized anti-CD70 antibodies and fragments and derivatives, that exert a cytotoxic, cytostatic or immunomodulatory on CD70 expressing cells, as well as pharmaceutical compositions and kits comprising the antibody, fragment or derivative. Also disclosed are methods for the treatment of CD70-expressing cancers and immunological disorders, comprising administering to a subject the CD70 binding agents or pharmaceutical compositions.
