PROBLEM TO BE SOLVED: To provide a determination system, a determination method, and a determination program capable of objectively grasping an effect of a medicine without imposing a strain on a subject.SOLUTION: The determination system is provided with: a correct information extraction unit that extracts, from digital information that includes a log of the subject who shows a sign of improvement of a symptom, correct information indicating a feature of the log relating to the improvement of the symptom an evaluation unit that evaluates, on the basis of correct information included in other digital information that includes a log of other subject, a degree of improvement of a symptom of the other subject and an effect estimation unit that estimates the effect of the medicine relative to the symptom according to an evaluation result obtained by the evaluation unit.COPYRIGHT: (C)2016,JPO&INPIT【課題】被験者に負担をかけず、薬剤の効果を客観的に把握できる判断システム、判断方法、及び判断プログラムを提供する。【解決手段】判断システムは、症状の改善の兆候がある被験者の経過記録を含むデジタル情報から症状の改善に関連する経過記録の特徴を示す正解情報を抽出する正解情報抽出部と、他の被験者の経過記録を含む他のデジタル情報に含まれる正解情報に基づいて、他の被験者の症状の改善の度合いを評価する評価部と、評価部の評価結果に応じ、症状に対する薬剤の効果を推定する効果推定部とを備える。【選択図】図1