BRADBURY MICHELLE S,YOO BARNEY,WIESNER ULRICH,MA KAI
申请号:
IN201617043358
公开号:
IN201617043358A
申请日:
2016.12.19
申请国别(地区):
IN
年份:
2017
代理人:
摘要:
Described herein are nanoparticle drug conjugates (NDCs) which in certain embodiments comprise a non toxic multi modality clinically proven silica based nanoparticle platform with covalently attached drug molecules/moieties. The nanoparticle drug conjugates (NDCs) demonstrate imaging capability and targeting ligands which efficiently clear through the kidneys. Furthermore the conjugates incorporate therapeutic agents for cancer detection prevention and/or treatment.