Yong Il KIM,Hayoung JEONG,Kyeong Soo KIM,Jae Hyun PARK,Jong Soo WOO
申请号：
US14778678
公开号：
US20160045444A1
申请日:
2014.04.30
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Provided is a composite formulation comprising: (i) a core including a first pharmacological component； and (ii) a film coating layer formed on a surface of the core, which contains rosuvastatin or a pharmaceutically acceptable salt thereof as a second pharmacological component and a polyvinyl alcohol-polyethylene glycol graft copolymer and polyvinyl alcohol as a coating material. In the composite formulation of the present invention, tension and fluidity of the film coating layer are excellent, and thus breakage and a defective ratio are low. Accordingly, a composite agent containing rosuvastatin effective to relieve and treat a hyperlipemia symptom, or its pharmaceutically acceptable salt can be provided with high efficiency, and is present in a composite formulation form, and thus compliance of a patient can be improved.
