Philip H. Coelho,William Busa,Jonathan Ellis,Dalip Sethi
申请号：
US16353071
公开号：
US20190282619A1
申请日:
2019.03.14
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Disclosed herein are methods for contacting in a closed container a host liquid including target cells, microbubble reagents comprising gas-core lipid-shelled microbubbles, and one or more antibodies or other ligands that bind to cell surface molecules on the target cells, wherein the one or more antibodies or other ligands are bound to the target cells or the microbubbles, wherein the contacting under conditions to produce target cells linked to microbubbles via the one or more antibodies or other ligands and activating the target cells to generate activated target cells.
