BREKKE OLE HENRIK,FREDRIKSEN AGNETE BRUNSVIK,AREFFARD ALI,LINDEBERG MONA MARI
申请号：
NZ62612412
公开号：
NZ626124A
申请日:
2012.12.20
申请国别(地区):
NZ
年份:
2016
代理人:
摘要：
Disclosed is a nucleic acid molecule encoding an amino acid chain comprising (1) a signal peptide, (2) a targeting unit, (3) a dimerization motif, and (4) an antigenic unit, said targeting unit comprising an amino acid sequence having at least 80 % sequence identity to the amino acid sequence 24-93 of SEQ ID NO:1, and an antigenic unit comprising an amino acid sequence of human papillomavirus (HPV) HPV16 and/or HPV18, preferably an antigenic unit derived from early proteins E6 and/or E7 of HPV16 and/or HPV18, which amino acid chain is able to form a homodimeric protein.
