Fusion proteins for HIV therapy

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专利权人:

THE ROCKEFELLER UNIVERSITY

发明人:

HO, DAVID,HUANG, YAOXING,PACE, CRAIG,SONG, RUI-JIANG,FANG, QING

申请号：

TW100141503

公开号：

TW201245228A

申请日:

2011.11.14

申请国别(地区):

TW

年份:

2012

代理人:

摘要：

Disclosed herein are fusion antibodies created to provide both an antigen-binding site that targets the CD4 receptor and an antigen-binding site that targets the HIV envelope. The fusion antibodies disclosed herein provide improved potency and breadth against HIV as compared to monospecific antibodies, and additionally provide high barrier against viral resistance. Also disclosed are pharmaceutical formulations and therapeutic methods utilizing such fusion proteins.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/