A dental appliance may have a pair of treatment portions and a pair of retaining surfaces that hold the treatment portions within the patient's mouth. With the treatment portions properly positioned, when the patient's mouth is in the maximum inter-cuspation position: (1) the upper canine teeth contact the upper surfaces of the treatment portions; (2) the lower teeth contact the lower surfaces of the treatment portions; and (3) no upper tooth physically contacts a lower tooth. As a result, bruxism and/or other ailments can be effectively treated.