Barbara L. Hempstead,Taeho Kim,Katrin Deinhardt,Moses Victor Chao,Jianmin Yang
申请号:
US13988193
公开号:
US20130336988A1
申请日:
2011.11.17
申请国别(地区):
US
年份:
2013
代理人:
摘要:
This disclosure relates to modulation of the interactions between proNTs and p75NTR/SorCS2 expressed on neuronal cells. Inhibition of such interactions is useful for reducing unwanted synaptic elimination, neurite pruning and/or other neuronal structural collapses, and for treating early stage and mild neurological disorders including mild cognitive impairment.