HARTUNG, INGO,INCE, STUART,KETTSCHAU, GEORG,THIERAUCH, KARL-HEINZ,BRIEM, HANS,TER LAAK, ANTONIUS M.,LIENAU, PHILIP
申请号：
CA2654105
公开号：
CA2654105C
申请日:
2007.06.12
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
The invention relates to substituted arylpyrazolopyridines according to the general formula (I) : in which A, B, D, E, Ra, R1, R2, R3, R4, R5 and q are as defined in the claims, and salts thereof, to pharmaceutical compositions comprising said substituted arylpyrazolopyridines, to methods of preparing said substituted arylpyrazolopyridines as well as the use thereof for manufacturing a pharmaceutical composition for the treatment of diseases of dysregulated vascular growth or of diseases which are accompanied with dysregulated vascular growth, wherein the compounds effectively interfere with Tie2 signalling.
