Patricia Culp,Helen Lam,Arnon Rosenthal,Seung-Joo Lee,Nels P. Nielson,Robert Pejchal
申请号:
US16054840
公开号:
US10711062B2
申请日:
2018.08.03
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind one or more epitopes within a CD33 protein, e.g., human CD33 or a mammalian CD33, and have improved and/or enhanced functional characteristics, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.