#$%^&*AU2017272233A120180104.pdf#####ll: rbr Interwovn NRPortbl DCC RBR 16126299 _.doc-06 12/2017 ABSTRACT Trisubstituted pyrido[3,2-d]pyrimidines, methods for preparation thereof and therapeutic uses thereof The present invention relates to compounds of the following general formula (1): , N R N wherein: - R1 is notably a group -NRaRb, Ra and Rb forming together with the nitrogen atom onto which they are bound, a heterocycle comprising from 5 to 30 atoms, - R2 is notably an aryl comprising from 5 to 30 atoms, and - R3 is notably an alkenyl comprising from 1 to 20 carbon atoms.