LEE, JU YOUNG,RYU, KEUN-HO,KIM, JAE-SUN,KIM, YONG-HYUK,SHIN, DONG CHUL,LEE, BONG-YONG,KANG, SANG-HWAN,LEE, HYUN JUNG,JUNG, HOECHUL,SHIN, YOUNG AH,PARK, EUISUN,AHN, JAESEUNG
申请号：
EP12811865
公开号：
EP2731949A4
申请日:
2012.07.13
申请国别(地区):
EP
年份:
2014
代理人:
摘要：
The present invention provides a novel 2-pyridyl substituted imidazole derivative, or a pharmaceutically acceptable salt or solvate thereof, which selectively inhibits the transforming growth factor-β (TGF-β) type I receptor (ALK5) and/or the activin type I receptor (ALK4)； a pharmaceutical composition comprising same as an active ingredient； and a use of the 2-pyridyl substituted imidazole derivative for the manufacture of a medicament for preventing or treating a disease mediated by ALK5 and/or ALK4 receptors in a mammal.
