BOEHRINGER INGELHEIM INTERNATIONAL GMBH;NEW YORK UNIVERSITY
发明人:
ALEXANDRA ZANIN-ZHOROV,MARYANNE BROWN,MICHAEL DUSTIN
申请号:
BRPI1014775
公开号:
BRPI1014775A2
申请日:
2010.04.28
申请国别(地区):
BR
年份:
2016
代理人:
摘要:
Disclosed is a method for treating a variety of diseases and disorders that are mediated or sustained through the activity of PKC-theta, including immunological disorders and atherosclerosis. Specifically, the invention relates to a method of treating an immunological disorder or atherosclerosis in a patient comprising treating blood from the patient, or a defined component of said blood, with an inhibitor of PKC-theta ex vivo and then re-administering the treated blood to the patient.