GlaxoSmithKline Intellectual Property Development Limited
发明人:
Bit, Rino Antonio,Brown, John Alexander,Humphreys, Philip G.,Jones, Katherine Louise
申请号：
HRP20191186
公开号：
HRP20191186T1
申请日:
2019.07.01
申请国别(地区):
HR
年份:
2019
代理人:
摘要：
Compounds of formula (I) and salts thereof:wherein R, R, R, Rare defined herein. Compounds of formula (I) and salts thereof have been found to inhibit the binding of the BET family of bromodomain proteins to, for example, acetylated lysine residues and thus may have use in therapy, for example in the treatment of autoimmune and inflammatory diseases, such as rheumatoid arthritis； and cancers.
