Guide wire devices and methods for their manufacture. Guide wire devices include an elongate guide wire member that includes at least one section fabricated from a substantially titanium-free Co—Ni—Cr—Mo alloy. The substantially titanium-free Co—Ni—Cr—Mo alloy exhibits superior stiffness (i.e., greater Youngs and shear moduli) as compared to stainless steel (e.g., 304V stainless steel) and nickel-titanium (Ni—Ti) and a greater yield strength as compared to stainless steel. Increasing the Youngs and shear moduli can significantly improve torque transmission and steerability of the guide wire device and increasing the yield strength can significantly improve the kink resistance of the guide wire device.
