Fuwai Hospital; Chinese Academy Of Medical Sciences And Peking Union Medical College
发明人:
申请号：
EP18923225.9
公开号：
EP3663394A1
申请日:
2018.06.19
申请国别(地区):
EP
年份:
2020
代理人:
摘要：
A method for preparing mesenchymal stem cell-derived exosomes on the basis of drug pretreatment, the method for preparing mesenchymal stem cell-derived exosomes comprising : using a statin to pretreat mesenchymal stem cells, and culturing the treated mesenchymal stem cells to collect exosomes secreted thereby. Also provided is an application of a statin in preparing a preparation for promoting the anti-apoptotic abilities and/or homing abilities of mesenchymal stem cells； and further provided is an application of a statin in preparing a preparation for promoting mesenchymal stem cells to secrete exosomes having myocardial infarction microenvironment-improving effects and/or myocardial repair abilities.
