An ambulatory assistance assembly includes a base unit that may be positioned on a support surface. The base unit may be aligned with a bed thereby facilitating a user to stand on the base unit. The base unit has a pair of rotatable disks to facilitate the user to align themselves with a wheelchair when the user is standing on the base unit. A handle unit is coupled to the base unit and the handle unit is gripped by the user when the user stands on the base unit thereby facilitating the user to selectively transfer themselves between the wheelchair and the bed.