KLAERNER, GERRIT,BUYSSE, JERRY M.,SHAO, JUN,OTTO, DAWN PARSELL
申请号:
CA3080143
公开号:
CA3080143A1
申请日:
2018.11.03
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
The present disclosure provides, inter alia, pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. In certain embodiments, the pharmaceutical compositions contain nonabsorbable compositions and may be used, for example, to treat diseases or other metabolic conditions in which removal of protons, the conjugate base of a strong acid and/or a strong acid from the gastrointestinal tract would provide physiological benefits such as normalizing serum bicarbonate concentrations and the blood pH in an animal, including a human.