A formula combining structure is provided: (1) x-a-ligante-b-z [1], wherein: (1) a and B are the same or different, and are independent: (a) a polypeptide, including sacol0029 (sections id.5 and 121-131) shown in any sequence described in table 24,1. Sacol0264 polypeptide (section 185)；A sacol0442 polypeptide shown in any sequence described in fig.22d (sections 29 and 82-92),1. Sacol0718 polypeptide (section 186)；A sack like peptide 0720 is shown in any sequence described by figs Ibid., sections 23i-j (Nos. 11 and 109-120),un polip ptido SACOL1353 (SEC ID N 187)un polip ptido SACOL1416 (SEC ID N 188)1. A kind of sacol1611 polypeptide (section 189)；5. A sacol1867 polypeptide, as shown in any sequence described in fig.25d (sections 152-164)；1. Sacol 1912 polypeptide (section 43)；1. Sacol 1944 polypeptide (section 190)；1. A sacl2144 polypeptide (section 191)；1. A kind of sacl2365 polypeptide (section 192)；1. Polypeptide sacol2385 (section 50) or polypeptide sacol2599 (section 193)；based on the Staphylococcus aureus COL (SACOL) genome nomenclature exposed in Reference Sequence in NCBI NC_002951.2； (b) a polypeptide encoded by a gene from the same operon as a gene encoding the polypeptide from (a)；(c) Polypeptides, including at least 13 consecutive (a) or (b) amino acid immune fragments；(d) A polypeptide containing at least 60% of the amino acid sequence, completely identical to any one of (a) to (c)；O (E) a polypeptide consisting of at least 13 consecutive amino acids in an immunovariant (a) to (c)；(2) Ligation agents are a series of amino acids, at least one of which is absent or missing； (3) x is a series of amino acids which are absent or at least one of which is absent； and (4) Z is a series of amino acids which are absent or at least one of which is absent. In addition, a variety of materials and toolkits are available for merging and using these merges, combinations and toolkits.Se proporciona un constructo de fusión de fórmula [1]: X-A-ligante-B-Z [1] donde: (1)
