Kim, Sunghoon,Choi, Jin Woo,Lee, Jin Young,Kim, Dae Gyu,Han, Gyoon Hee,Yang, Jee Sun,Lee, Chul Ho
申请号：
AU2010316076
公开号：
AU2010316076A1
申请日:
2010.11.05
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
The present invention relates to a novel use of benzo-heterocycle derivatives, and more particularly, to a composition for preventing and treating cancer, comprising benzo-heterocycle derivatives or pharmaceutically acceptable salts thereof as active ingredients. The inventors of the present invention have found that KRS interacts with 67LR to promote the migration of cancer (or tumor) cells and thus affects the metastasis of cancer, and also have identified that the substance which inhibits the interaction between the KRS and 67LR suppresses the metastasis of cancer cells, and thus can be used for preventing and treating cancer. Accordingly, the composition of the present invention suppresses the metastasis of cancer, and therefore provides a novel means for preventing and treating cancer.
