An orthopedic device includes a lateral wedge positionable under a foot of a user. The lateral wedge has posterior and anterior ends, and upper and lower surfaces. First and second sides extend between the upper and lower surfaces. A thickness is defined between the upper and lower surfaces that tapers from the first side toward the second side such that the lateral wedge provides a lift under the foot to unload pressure from an affected compartment of the knee by supporting a one side of the foot in an elevated position relative to the other. At least one trim line extends in a direction between the posterior and anterior ends. The lateral wedge is trimmable along the at least one trim line to vary or control the amount of lift provided by varying the thickness of the lateral wedge along the first side relative to the second side.