INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY;SNU R&DB FOUNDATION
发明人:
Park Tae Sun,Jeong Lak Shin
申请号：
US201515513072
公开号：
US10100011(B2)
申请日:
2015.09.22
申请国别(地区):
美国
年份:
2018
代理人:
Norton Rose Fulbright US LLP
摘要：
The present invention relates to a novel pentadienoyl piperidine derivative, a pharmaceutical composition containing the same for prevention or treatment of metabolic diseases, and a functional food composition using the same for improvement or relief of metabolic diseases. The pentadienoyl piperidine derivative of the present invention inhibits the differentiation of preadipocytes, reduces body weight, visceral fat, blood lipid levels, and blood glucose levels, improves a blood liver function index, and suppresses metabolic inflammation responses. Thus, ultimately, the derivative can be usefully used as a medicine or a functional food composition, which exhibits the preventive or therapeutic activity for metabolic diseases selected from the group consisting of obesity, diabetes, dyslipidemia, fatty liver and insulin resistance syndrome.
