HUANG, TAISHENG,XUE, CHU-BIAO,WANG, ANLAI,KONG, LING,YE, HAI FEN,YAO, WENQING,RODGERS, JAMES D.,SHEPARD, STACEY,WANG, HAISHENG,SHAO, LIXIN,LI, HUI-YIN,LI, QUN
申请号:
CA2792508
公开号:
CA2792508C
申请日:
2011.03.09
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
The present invention provides piperidin-4-yl azetidine derivatives, as well as their compositions and methods of use, that modulate the activity of Janus kinase 1 (JAK1) and are useful in the treatment of diseases related to the activity of JAK1 including, for example, inflammatory disorders, autoimmune disorders, cancer, and other diseases.