N-hydroxy-3-(4-{3-phenyl-s-oxo-propenyl}-phenyl)-acrylamide derivatives and related compounds as histone deacetylase inhibitors for the treatment of cancer
MINUCCI, SAVERIO,MAI, ANTONELLO,THALER, FLORIAN,GAGLIARDI, STEFANIA,PAIN, GILLES,COLOMBO, ANDREA
申请号：
AU2007233732
公开号：
AU2007233732B2
申请日:
2007.03.30
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
New histone deacetylase inhibitors according to the general formula (I) wherein: Q is a bond, CH, CH-NRR, NR or oxygen, X is CH or nitrogen, Y is a bond, CH, oxygen or NR, Z is CH or nitrogen, R, R are, independently, hydrogen, halogen, C-C alkyl or C-C haloalkyl, R, R are, independently, hydrogen or C-C alkyl, and R, R, R and R are as further defined in the specification.
