Jonathan Moss,Mark Lingen,Patrick A. Singleton,Joe G. N. Garcia
申请号:
US12723339
公开号:
US08518962B2
申请日:
2010.03.12
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Embodiments of the invention provide methods of attenuating, e.g., inhibiting or reducing, cellular proliferation and migration, particularly endothelial cell proliferation and migration, including that associated with angiogenesis, as well as attenuating cancerous tumor growth and metastasis, using opioid antagonists, including, but not limited to, those that are peripherally restricted antagonists.