Riggs-Sauthier, Jennifer,Deng, Bo-Liang,Riley, Timothy A.
申请号:
AU2010276244
公开号:
AU2010276244A1
申请日:
2010.07.21
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
The invention provides conjugates wherein the opioid agonists, hydroxycodone (oxycodone) and hydrocodone (dihydrocodeiπone) are covalently attached to poly(ethylene glycol) oligomers. A conjugate of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from those of the opioid agonist not attached to the PEG oligomers.