Marc Lukacs;Francis Stuart Foster;Paul A. Dayton;Ryan Gessner;Hyunggyun Lee
发明人:
Paul A. Dayton,Ryan Gessner,Hyunggyun Lee,Marc Lukacs,Francis Stuart Foster
申请号：
US13393500
公开号：
US20120220869A1
申请日:
2010.09.07
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Systems, methods, and computer readable media for high-frequency contrast imaging and image-guided therapeutics are disclosed. According to one aspect a method for high frequency contrast imaging and image-guided therapeutics includes: providing ultrasound of a first frequency bandwidth, directed toward the volume to be imaged, the volume containing a carrier having non-linear acoustical properties, wherein the ultrasound of the first frequency bandwidth causes the carrier to generate ultrasound of a second frequency bandwidth that is different from the first frequency bandwidth； receiving, from the volume to be imaged, ultrasound of the second frequency bandwidth； and using the received ultrasound of the second frequency bandwidth to generate an image of the volume to be imaged, wherein the components of the second frequency bandwidth that are detected are of a frequency greater than 20 MHz. According to another aspect, ultrasound at a first frequency bandwidth enables imaging of a target, and ultrasound at a second frequency bandwidth mediates drug or gene delivery to a portion of the target, as guided by the image provided by the first frequency.
