BONNERT, ROGER VICTOR,LUKER, TIMOTHY JON,PATEL, ANIL,RIGBY, AARON,BONNERT, Roger Victor,LUKER, Timothy Jon,PATEL, Anil,RIGBY, Aaron
申请号:
RSP20140008
公开号:
RS53129B
申请日:
2008.07.01
申请国别(地区):
RS
年份:
2014
代理人:
摘要:
The present invention concerns a pharmaceutical composition formed by the synergistic combination of a selective serotonin reuptake inhibitor, such as the active principle: Paroxetine hydrochloride hemihydrate and an agent belonging to the triazolobenzodiazepine group, such as the active principle: Alprazolam, as well as pharmaceutically acceptable excipients; which are formulated in a single dosing unit to be administered by oral means, said unit being prescribed for the treatment and control of major depressive episodes, symptoms of Obsessive-Compulsive disorder (OCD), panic attacks with or without agoraphobia, generalized anxiety disorders, social phobia and post-traumatic stress disorder.Jedinjenje formule (I):naznačeno time što je smeša (2S)-2-({3'-hloro-4'-[(2,2-dimetilpirolidin-1-il)karbonil]-5-fluorobifenil-2-il}oksi)propanske kiseline i (2R)-2-({3'-hloro-4'-[(2,2-dimetilpirolidin-1-il)karbonil]-5-fluorobifenil-2-il}oksi)propanske kiseline, ili njihovih farmaceutski prihvatljivih solvata ili farmaceutski prihvatljivih soli ili solvata farmaceutski prihvatljivih soli.Prijava sadrži još 19 patentnih zahteva.