The present disclosure provides drug containers that allow for the mixing of one or more substances prior to drug injection and drug delivery pumps incorporating such drug containers. The drug delivery pumps may be wearable by a user. Mixing of the two or more substances contained within separate, mutable chambers is initiated by transforming an outer barrel distal seal (524) from a first position in which it covers ports (518) extending through an inner barrel (510) to a second position in which the outer barrel distal seal (524) does not cover the ports. Mixing is induced by forcing the contents of the outer chamber (526) through the ports and into the inner chamber, thereby by mixing with the contents of the inner chamber. After mixing of the substances is complete the mixed contents of the inner chamber are forced out of the inner chamber by distal displacement of an injection seal (512) located within the inner barrel. The contents may be delivered through a sterile pathway connection (300) and sterile fluid conduit (320) into the body of the patient. By providing these drug containers and drug delivery pumps that incorporate them, medicaments may be stored as two or more separate constituents and mixed at or near time of delivery.La présente invention concerne des récipients de médicament qui permettent le mélange dune ou de plusieurs substances avant linjection de médicament, et des pompes dadministration de médicament comprenant de tels récipients de médicament. Les pompes dadministration de médicament peuvent être portées par un utilisateur. Le mélange des deux ou plus de deux substances contenues dans des chambres modifiables et distinctes est commencé par transformation dun joint détanchéité distal de tube externe (524) dune première position, dans laquelle il recouvre des orifices (518) sétendant à travers un tube interne (510), à une seconde position dans laquelle le joint détanchéité distal de tube externe (524) ne recouvre pas les orifices. Le mélange
