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Therapeutic compositions and applications that comprise nucleic acids and adoptively transferred immune cell
专利权人:
HANGZHOU CONVERD CO., LTD.;SYNIMMUNE, INC.
发明人:
Yafei Hou,Fang Hu,Jipo Sheng,Xiankui Tan,Can Chen
申请号:
US16798465
公开号:
US20200289567A1
申请日:
2020.02.24
申请国别(地区):
US
年份:
2020
代理人:
摘要:
A therapeutic agent and method of administering the therapeutic agent for the treatment of tumors and/or cancers of a subject, the therapeutic agent comprising a first pharmaceutical composition comprising a first active ingredient in a first druggable vehicle, wherein the first active ingredient comprises a nucleic acid encoding a labelling polypeptide comprising one or more antigenic epitope peptides and/or encoding a MHC protein; a second pharmaceutical composition comprising a second active ingredient in a second druggable vehicle, wherein the second active ingredient comprises immune cells purified from peripheral blood or from tumor tissue and are cultured in vitro; wherein the nucleic acid when administered to the subject as part of the pharmaceutical composition causes the tumor cells and/or cancer cells of the subject to express the one or more antigenic epitope peptides to elicit an immune response of the immune cells.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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