Xiaoxia Cui,Gregory Davis,Philip D. Gregory,Michael C. Holmes,Edward J. Weinstein
申请号：
US13066802
公开号：
US20120017290A1
申请日:
2011.04.25
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Disclosed herein are methods and compositions for genome editing of a Rosa locus, using fusion proteins comprising a zinc-finger protein and a cleavage domain or cleavage half-domain. Polynucleotides encoding said fusion proteins are also provided, as are cells comprising said polynucleotides and fusion proteins.
