A garment includes a vertical opening and a transverse flap on the front panel thereof for securing an external portion of a central line or catheter having at least two distal lumens or branches. The external portion of the catheter extends through a gap between a pair fasteners of the vertical opening. In order to secure the catheter, the flap includes a stopper that is fastened to front panel such that the stopper is located between the distal branches of the catheter. If one or both of the distal branches are pulled or tugged, a junction or transition area of the catheter is pressed against the stopper and limits further motion of the catheter to prevent dislodgement thereof. The flap further includes a series of fasteners for releasably coupling a free edge thereof onto the front panel to house the external portion of the catheter under the closed flap.