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Retrovirus vector
专利权人:
ユーシーエル ビジネス パブリック リミテッド カンパニー
发明人:
ヴィンク,コンラッド,ハウ,スティーブン,ヴィンク,コンラッド,ハウ,スティーブン
申请号:
JP2016524423
公开号:
JP6525986B2
申请日:
2014.10.16
申请国别(地区):
JP
年份:
2019
代理人:
摘要:
There is disclosed a retroviral vector comprising a primer binding site, a long terminal repeat and an RNA packaging sequence, wherein the RNA packaging sequence is located 3′ of the long terminal repeat and no long terminal repeat is located 3′ of the RNA packaging sequence such that reverse transcription initiated at the primer binding site does not lead to reverse transcription of the RNA packaging sequence into vector DNA in a target cell. Also described is a host cell, a virion, a pharmaceutical composition, a method and uses including or involving the vector described above. Further, a cell or transgenic animal produced by using the vector is also described.
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中国工程科技知识中心
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